Senior Scientist CAR T and TCR Biology

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

The CAR T and TCR Biology team is seeking a highly motivated immunologist to lead preclinical in vitro activities for optimizing and engineering lead T cell therapeutic candidates. The successful candidate will have in depth conceptual understanding of tumor-associated T cell biology and be able to identify relevant assays, as well as recognize the need for novel technologies, for assessing functionality of the engineered T cells. This is a supervisory position and is ideal for the innovative scientist who is driven and passionate about cell therapy in a fast-paced, collaborative environment.

Responsibilities include but are not limited to:


Identification and conception of novel mechanisms for improving T cell function and leading design and characterization activities to enable science-driven decision making

Designing, implementing and overseeing critical studies required to drive hypothesis-driven research through interpretation of complex experiments and develop assays and research tools.

Application of extensive knowledge of T cell biology including activation pathways, signaling pathways and antigen-specific differentiation

Provide scientific leadership on cross-functional assignments

Manages and/or coordinates workflow on projects

Will provide recommendations on department-level strategic decisions

Represent the company in external settings and work with external as well as internal collaborators

Mentoring direct reports to provide guidance for outlining studies required for project advancement


Qualifications:


Ph.D. in immunology, immune-oncology or tumor immunology with at least 3 years of successful postdoctoral experience as demonstrated by strong publication record plus at least 3 years of experience in an industry setting or a M.S. with a minimum of 12 years of relevant work experience or B.S. with minimum of 14 years of relevant work experience in T cell immunology

Experience with in vitro technologies typically employed to assess T cell functionality including but not limited to MSD, IncuCyte-based assays, multi-parameter flow cytometry for phenotypic characterization of T cells, T cell activation assays, T cell proliferation analysis, imaging

T cell biology expert able to apply skills, theoretical knowledge and experience to provide scientific direction and approach to projects and challenges

Able to recognize problems and recommend/develop appropriate solutions

Self-motivated and focused with project management-oriented thinking; able to work on multiple projects in a matrix environment

Ability to work productively as both team member and as individual contributor

Strong communication skills for working with cross-functional teams as well or cross-departmental colleagues

Requires strong organizational skills to ensure thorough and timely documentation of experiments, including those of their direct reports, and preparation of data for compiling reports

Able to conceptualize broad impact of research programs and personal activities

Supervisory experience is a plus


Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Company info

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