Research Investigator I/II Drug Product Development

Profile

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Bristol-Myers Squibb is a global biopharmaceutical company firmly focused on its mission to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. Our BioPharma strategy uniquely combines the reach and resources of a major pharma company with the entrepreneurial spirit and agility of a successful biotech company. We focus on developing our pipeline drugs with innovative, differentiated, patient-centric medicines for patients with severe unmet medical need.

We are looking to hire a talented, highly motivated individual as a Research Investigator in Drug Product Development department to conduct innovative drug delivery research to address delivery issues covering a wide range of modalities (small molecules, peptides, biologic and nucleic acids) delivered by injectable, oral or alternate routes of administration. The central focus of this role will be to experimentally explore novel delivery strategies to resolve specific delivery problems, conduct bioperformance testing, and build in vitro-in vivo understanding to enable the design and development of differentiated drug products for clinical testing.

Job Responsibilities:


Support development of new molecular entities through conducting biopharmaceutical research on innovative drug delivery systems using in vitro and in vivo methodology.
Work collaboratively with formulators to explore novel formulation technologies such as extended release polymer, gel, or lipid-based injectables, targeted drug delivery and new routes of administration
Design and conduct bioperformance experimentation such as in vitro drug release and contribute to pharmacokinetic (PK) studies in animals.
Collaborate with team members to understand material characteristics of the drug delivery system, conduct analytical quantitation, and assess the impact on in vitro & in vivo performance.
Work collaboratively and effectively in a team environment to execute studies in a timely manner, conduct data analysis and present findings.
Broadly apply drug delivery concepts to a variety of modalities (small molecules, peptides, biologics, and nucleic acids) that can span a variety of routes of administration.


Requirements/Education:


Ph. D. with 0-4 years of experience in pharmaceutical sciences, biotechnology or related field. The applicant must have solid fundamental knowledge of drug delivery and biopharmaceutics through academic or prior industry experience.
Hands on experience with the development of a polymer or lipid-based drug delivery system such as micro/nano particles, polymer gels, liposomes/lipid nanoparticles, along with methodology to assess performance in vitro and in vivo PK is required.
Independent study conduct and proficiency in analyzing / interpreting experimental data, running analytical techniques such as HPLC/ UPLC-UV, size-exclusion chromatography, UV/fluorescence spectrometry, and common characterization techniques is highly desirable.
Familiarity with the biology/physiology of the site of delivery and the interaction with the drug delivery system is preferred.
The candidate must possess strong verbal, written, and interpersonal communication skills to function as an effective team player in a highly collaborative matrix team environment, and interface with internal and external partners to drive team deliverables forward.


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Company: Bristol-Myers Squibb

Req Number: R1526913_EN

Updated: 2020-06-29 00:00:00.000 UTC

Location: New Brunswick,New Jersey

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

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